Manchester City will be looking to reach the semi-finals of the Champions League for the second year in a row where they will face Atletico Madrid's Diego Simeone in a two-legged match.
With the busy schedule of April - which includes a double face-off approach - Pep Guardiola will be aiming to lead well back to Wanda Metropolitano in the second leg next week.
The Spanish champions have shown that they are not pupuvers. Currently in a six-game winning streak, Simeone's side will be thrilled to see a stunning Last 16 win against Manchester United.
City already do not have full-back Ruben Dias - who is still suffering from an injury - and regular Kyle Walker is serving his final three-match suspension.
However, there are other suspension concerns that could have a direct impact on the second leg.